Jean-René Lèquepeys received his engineering degree in 1983 from Supélec and taught physics for 2 years in Ouarzazate, Morocco. He joined CEA in October 1985, in Saclay, within the Central Security Office, in the laboratory for the evaluation of means of detection and intrusion ; In 1987, he hold the head of the laboratory. In 1993, he was recruited by DSYS, at LETI in Grenoble, as an R & D engineer, in the field of image processing. He then lead projects in the field of "Telecom" at LETI before getting the head of "Telecom, Communicating Objects and Smart Card" programs in 1999, within the team of Jean-Frédéric Clerc. In 2005, he took in charge the Circuits Design Department at LETI / DSYS, and then created, in partenership with the Ecole des Mines de Saint-Etienne, a laboratory dedicated to electronic components safety analysis located in Gardanne (Paca). In 2010, from the common initiative of both LETI and LIST Directors, he launched DACLE division, relying on original bi-site and bi-institute model, and focusing on Electronic Architectures, Integrated Circuit Design and Embedded Software.. He participated to the creation of the Division DCOS (Division of Silicon Components) in 2011, and then lead the division until the end of 2017, when he got back to the head of DACLE division in 2018. In 2000, Jean-René Lèquepeys received the famous award from SEE "Grand Prix de l'électronique Général Ferrié" for his work in the telecommunications field. He is the author of about fifteen patents in this field.
In 2019 he was appointed Deputy Director in charge of programs at LETI and Deputy Director of the Director of LETI.